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KMID : 1134820080370111422
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Journal of the Korean Society of Food Science and Nutrition
2008 Volume.37 No. 11 p.1422 ~ p.1426
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Study on the Mineral and Heavy Metal Contents in the Hair of Preschool Aged Autistic Children
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Jung Myung-Ae
Jang Hyun-Seo
Park Eun-Ju
Lee Han-Woo
Choi Jeong-Hwa
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Abstract
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The purpose of this study was to test characteristics between normal and autistic children via comparison of nutrient intakes, hair mineral, blood free radical, and serotonin contents. A total of 50 children aged 3-9 were divided into two main groups of normal control children (n=22) and autistic children (n=28) tested by child psychiatrist. The nutrient intakes by 24-hour recall method were no significantly different between the two groups. The concentrations of toxic mineral, such as cadmium (Cd) and lead (Pb) in hair of autistic children were significantly higher, while concentration of antioxidant mineral (Cu, Zn, Fe) was lower than that of normal children. The autistic children had significantly higher concentrations of blood free radical than that of normal children. No significant difference was observed in serotonin concentration between the two groups. Our results suggest a possible role of increased toxic mineral and free radical, both of which may be relevant to the pathophysiology of autism in children with developmental delay.
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KEYWORD
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nutrient intakes, hair mineral, free radical, serotonin, autistic children
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